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planar multielectrode recording setup  (Alpha MED Scientific)


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    Alpha MED Scientific planar multielectrode recording setup
    Planar Multielectrode Recording Setup, supplied by Alpha MED Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/planar+multielectrode+recording+setup/pm39792668-428-26-30?v=Alpha+MED+Scientific
    Average 90 stars, based on 1 article reviews
    planar multielectrode recording setup - by Bioz Stars, 2026-07
    90/100 stars

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    planar multielectrode recording setup med64 system  (Alpha MED Scientific)
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    Alpha MED Scientific planar multielectrode recording setup med64 system
    Hippocampal LTP is increased in Trim3 −/− mice. (A and B) Spontaneous excitatory (A) and inhibitory (B) synaptic transmission are unaffected in Trim3 −/− mice. Excitatory synaptic currents (mEPSC) and inhibitory synaptic currents (mIPSCs) were recorded from hippocampal slices. Frequency, amplitude, rise time, and decay time of both excitatory and inhibitory currents were unaffected in Trim3 −/− mice compared with wild-type controls (means ± SEM, n = 6–8 for EPSCs, n = 10 for IPSCs). (C) LTP was induced in acute hippocampal slices using a single stimulation electrode in the Schaffer collateral pathway, and field excitatory postsynaptic potentials (fEPSPs) were recorded using an 8 × 8 <t>multielectrode</t> array (black dots) in the CA1 area. Bar, 400 µm. (D) Example field EPSP traces from a Trim3 −/− mice and a wild-type control before (gray) and after (black) tetanus stimulation indicate stronger potentiation in Trim3 −/− mice. (E) Averaged fEPSP data show enhanced LTP in Trim3 −/− animals, in particular in the first 30 min after theta burst stimulation (TBS). (F) Quantification of the mean amount of potentiation at 10–20 min and 20–30 min after TBS show a significant increase in Trim3 −/− mice (means ± SEM, two-tailed t test, *, P < 0.05, n = 15/16 slices obtained from 9/10 animals per genotype).
    Planar Multielectrode Recording Setup Med64 System, supplied by Alpha MED Scientific, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/planar+multielectrode+recording+setup/pmc04639863-351-1-5?v=Alpha+MED+Scientific
    Average 90 stars, based on 1 article reviews
    planar multielectrode recording setup med64 system - by Bioz Stars, 2026-07
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    		  Buy from Supplier

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    Hippocampal LTP is increased in Trim3 −/− mice. (A and B) Spontaneous excitatory (A) and inhibitory (B) synaptic transmission are unaffected in Trim3 −/− mice. Excitatory synaptic currents (mEPSC) and inhibitory synaptic currents (mIPSCs) were recorded from hippocampal slices. Frequency, amplitude, rise time, and decay time of both excitatory and inhibitory currents were unaffected in Trim3 −/− mice compared with wild-type controls (means ± SEM, n = 6–8 for EPSCs, n = 10 for IPSCs). (C) LTP was induced in acute hippocampal slices using a single stimulation electrode in the Schaffer collateral pathway, and field excitatory postsynaptic potentials (fEPSPs) were recorded using an 8 × 8 multielectrode array (black dots) in the CA1 area. Bar, 400 µm. (D) Example field EPSP traces from a Trim3 −/− mice and a wild-type control before (gray) and after (black) tetanus stimulation indicate stronger potentiation in Trim3 −/− mice. (E) Averaged fEPSP data show enhanced LTP in Trim3 −/− animals, in particular in the first 30 min after theta burst stimulation (TBS). (F) Quantification of the mean amount of potentiation at 10–20 min and 20–30 min after TBS show a significant increase in Trim3 −/− mice (means ± SEM, two-tailed t test, *, P < 0.05, n = 15/16 slices obtained from 9/10 animals per genotype).

    Journal: The Journal of Cell Biology

    Article Title: Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels

    doi: 10.1083/jcb.201506048

    Figure Lengend Snippet: Hippocampal LTP is increased in Trim3 −/− mice. (A and B) Spontaneous excitatory (A) and inhibitory (B) synaptic transmission are unaffected in Trim3 −/− mice. Excitatory synaptic currents (mEPSC) and inhibitory synaptic currents (mIPSCs) were recorded from hippocampal slices. Frequency, amplitude, rise time, and decay time of both excitatory and inhibitory currents were unaffected in Trim3 −/− mice compared with wild-type controls (means ± SEM, n = 6–8 for EPSCs, n = 10 for IPSCs). (C) LTP was induced in acute hippocampal slices using a single stimulation electrode in the Schaffer collateral pathway, and field excitatory postsynaptic potentials (fEPSPs) were recorded using an 8 × 8 multielectrode array (black dots) in the CA1 area. Bar, 400 µm. (D) Example field EPSP traces from a Trim3 −/− mice and a wild-type control before (gray) and after (black) tetanus stimulation indicate stronger potentiation in Trim3 −/− mice. (E) Averaged fEPSP data show enhanced LTP in Trim3 −/− animals, in particular in the first 30 min after theta burst stimulation (TBS). (F) Quantification of the mean amount of potentiation at 10–20 min and 20–30 min after TBS show a significant increase in Trim3 −/− mice (means ± SEM, two-tailed t test, *, P < 0.05, n = 15/16 slices obtained from 9/10 animals per genotype).

    Article Snippet: A planar multielectrode recording setup (MED64 system; Alpha Med Sciences) was used to record field EPSP (fEPSP) and elicit LTP as previously described ( ).

    Techniques: Transmission Assay, Control, Two Tailed Test